Bis[2-(1H-1,2,3-benzotriazol-1-yl)acetic acid-κN 3]dichloridozinc(II)

In the title complex, [ZnCl2(C8H7N3O2)2], the ZnII atom is coordinated by two chloride ions and two N atoms in a distorted tetra­hedral coordination environment. In the crystal structure, mol­ecules are linked by inter­molecular C—H⋯O and O—H⋯O hydrogen bonds, forming a three-dimensional network

Creating hospital-specific customized clinical pathways by applying semantic reasoning to clinical data

AbstractObjectiveClinical pathways (CPs) are widely studied methods to standardize clinical intervention and improve medical quality. However, standard care plans defined in current CPs are too general to execute in a practical healthcare environment. The purpose of this study was to create hospital-specific personalized CPs by explicitly expressing and replenishing the general knowledge of CPs by applying semantic analysis and reasoning to historical clinical data.MethodsA semantic data model was constructed to semantically store clinical data. After querying semantic clinical data, treatment procedures were extracted. Four properties were self-defined for local ontology construction and semantic transformation, and three Jena rules were proposed to achieve error correction and pathway order recognition. Semantic reasoning was utilized to establish the relationship between data orders and pathway orders.ResultsA clinical pathway for deviated nasal septum was used as an example to illustrate how to combine standard care plans and practical treatment procedures. A group of 224 patients with 11,473 orders was transformed to a semantic data model, which was stored in RDF format. Long term order processing and error correction made the treatment procedures more consistent with clinical practice. The percentage of each pathway order with different probabilities was calculated to declare the commonality between the standard care plans and practical treatment procedures. Detailed treatment procedures with pathway orders, deduced pathway orders, and orders with probability greater than 80% were provided to efficiently customize the CPs.ConclusionsThis study contributes to the practical application of pathway specifications recommended by the Ministry of Health of China and provides a generic framework for the hospital-specific customization of standard care plans defined by CPs or clinical guidelines

Responses of soil nitrogen mineralization to temperature and moisture in alpine ecosystems on the Tibetan Plateau

AbstractThe responses of soil net nitrogen (N) mineralization to temperature and moisture were investigated in four alpine ecosystems of forest, shrub, meadow and steppe by laboratory incubation method with undisturbed soil cores on the Tibetan Plateau. The results indicated the soil net N mineralization varies greatly between alpine ecosystems. The soil net N mineralization rate in three incubating moisture of forest ecosystem rose markedly, and that of meadow ecosystem rose gently from temperature of 5°C to 35°C, while that of shrub and steppe ecosystems increased from temperature of 5°C to 25°C and reduced from temperature of 25°C to 35°C. At the same incubating temperature, the soil net N mineralization of four alpine ecosystems increased in the middle moisture and deceased in the low or high moisture

(E)-2-[2-(2-Thien­yl)vin­yl]-1H-1,3-benzimidazole

In the title compound, C13H10N2S, the dihedral angle between the imidazole and thio­phene rings is 16.89 (19)°, and the double bond adopts an E configuration. In the crystal structure, N—H⋯N hydrogen bonds link the mol­ecules into rows along b. There is also evidence of weak C—H⋯S inter­actions